Pick a flight that is during the baby’s nap time. Hopefully, if they sleep the entire flight you can avoid changing diapers on the plane.
Sit in an aisle seat. When you book your ticket make sure you select an aisle seat, so you can easily get up when needed.
I recommend changing your baby’s diaper before you board. Because you are traveling with a young child, you will be one of the first to board.
It will depend on what kind of airplane you are traveling on. The bigger the plane, the higher the chance that there will be a changing table on the plane.
If your child is still very small, and you have a companion with you, or your co-passenger wants to assist you generously, then you can change the baby on your lap instead.
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